Support optimal methylation, energy production, and nervous system health with Natural Factors BioCoenzymated Methylfolate Folate + B12 1000/50 mcg, 60 Ct. This advanced formula delivers metabolically active forms of Folate (5-MTHF) and Vitamin B12 (methylcobalamin) to ensure superior absorption and utilization by the body.
Unlike standard folic acid, this supplement contains (6S)-5-methyltetrahydrofolate (5-MTHF) from Quatrefolic®, the biologically active coenzyme form of folate. Because B vitamins must be converted into their active coenzyme forms before the body can use them, this bio-coenzymated formula helps bypass common metabolic conversion challenges.
Key Benefits
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Provides 1000 mcg active 5-MTHF (Methylfolate)
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Includes 50 mcg Methylcobalamin (active B12)
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Supports healthy methylation processes
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Promotes red blood cell formation
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Helps maintain nervous system health
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Supports energy metabolism
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BioCoenzymated™ for enhanced absorption
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Convenient once-daily capsule
Folate and vitamin B12 play critical roles in DNA synthesis, neurological function, and homocysteine metabolism. The active coenzyme form of folate — 5-MTHF — works directly with enzymes in the body to promote essential biochemical reactions. Without these active coenzymes, enzymes cannot efficiently carry out life-sustaining metabolic processes.
This formula is ideal for individuals who prefer methylated B vitamins or those who may have difficulty converting folic acid into its active form.
Medicinal Ingredients (Per Capsule):
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Folate (from (6S)-5-methyltetrahydrofolate glucosamine salt, Quatrefolic®) – 1000 mcg
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Vitamin B12 (Methylcobalamin) – 50 mcg
Non-Medicinal Ingredients:
Lactose, microcrystalline cellulose, croscarmellose sodium, Farm Fresh Factors™, vegetable-grade magnesium stearate (lubricant).
Directions for Use
Take 1 capsule daily or as directed by a healthcare professional.
Statements regarding dietary supplements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Always read labels, warnings, and directions before use and consult your healthcare provider if you suspect a medical condition.






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